Coronary disease & ACSCohort study
Safety, Feasibility, and Diagnostic Yield of Invasive Coronary Function Testing
- Quality improvement study using a prospective observational registry
- multicentre (15 hospitals: 2 tertiary, 13 nontertiary)
Authors' conclusion
This study found that a CFT was feasible and safe to perform in both tertiary and nontertiary centers with a high diagnostic yield.
Study context
- Population
- Patients with angina and no obstructive CAD clinically referred for invasive coronary function testing (coronary function test (CFT)), Netherlands, December 2020–January 2024978 (81%) female
- Participants
- 1,207 patients
- Outcome
- Prevalence of coronary vasomotor dysfunction endotypes and overall safety of CFT
Main finding
As reported in the abstract
Prevalence of coronary vasomotor dysfunction
Coronary vasomotor dysfunction
78%
Observational data: associations, not effects.
Safety
Complications of CFT
- Major complications
- 11 (0.9%)
- Minor complications
- 10 (0.8%)
- Major complications definitely related to CFT
- 3
- Procedural death, MI or stroke
- 0
- No differences in complications between tertiary and nontertiary centres
- all minor complications definitely related to CFT
Original publication
Safety, Feasibility, and Diagnostic Yield of Invasive Coronary Function Testing. JAMA Cardiol. Published 1 April 2025. doi:10.1001/jamacardio.2024.5670
Summarised from the published abstract; every number is checked against it