Arrhythmias & electrophysiology
Safety, feasibility, and prognostic value of stress perfusion cardiovascular magnetic resonance (CMR) in patients with MR-conditional pacemaker
Authors' conclusion
Stress CMR is safe, feasible and has a good discriminative prognostic value in consecutive patients with PM.
Study context
- Population
- Consecutive patients with MR-conditional pacemaker referred for vasodilator stress CMR at 1.5 T, 2008–2021273 completed follow-up
- Participants
- 304 patients
- Exposure
- Ischaemia or late gadolinium enhancement (LGE) vs none on stress CMR
- Outcome
- MACE:
- Cardiac death
- Non-fatal MI
- Follow-up
- Median 7.1 [5.4-7.5] years
Methodological detailsbi-centre, consecutive patients, blinded image-quality rating
- Bi-centre
- Consecutive patients
- Blinded image-quality rating
Main finding
As reported in the abstract
Prognostic value of CMR parameters for MACE
Hazard ratio (95% CI)P value
Ischaemiaunadjusted
11.71(4.60–28.2)
P < 0.001LGEunadjusted
5.62(2.02–16.21)
P < 0.001Ischaemiaadjusted for traditional risk factors
5.08(2.58–14.0)
P < 0.001LGEadjusted for traditional risk factors
2.28(2.05–3.76)
P < 0.001- Major adverse cardiovascular events (MACE)
- 32 (11.7%)
Observational data: associations, not effects.
Further findings
Image quality
- Segments rated good or excellent
- 84.9%
Safety
Tolerance and pacemaker function
- Well tolerated; no significant change in lead thresholds or pacing parameters
Original publication
Safety, feasibility, and prognostic value of stress perfusion CMR in patients with MR-conditional pacemaker. Eur Heart J Cardiovasc Imaging. Published 10 October 2022. doi:10.
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