Screening for anxiety and depression in clinical practice: translating scores from World Health Organization-5/Anxiety Symptom Scale-2/Major Depression Inventory-2 to Hospital Anxiety and Depression Scale
Authors' conclusion
Our study shows that it is feasible to use crosswalks between HADS-A and WHO-5/ASS-2 and HADS-D and WHO-5/MDI-2 for screening cardiac patients across diagnoses for anxiety and depression in clinical practice.
Study context
- Population
- Danish patients with a hospital contact and discharge diagnosis of ischaemic heart disease, HF, heart valve disease or AF in 2018 ('Life with a heart disease' survey)10,000 invited
- Participants
- 4,346 patients
- Exposure
- WHO-5/ASS-2 and WHO-5/MDI-2 vs Hospital Anxiety and Depression Scale (HADS)
- Outcome
- Whether WHO-5/ASS-2 and WHO-5/MDI-2 can replace HADS as screening tool for anxiety and depression, and feasibility of crosswalks (translation tables)
Methodological detailsitem response theory (bi-factor item response theory (IRT) models), national survey
- Item response theory (bi-factor IRT models)
- National survey
Main finding
As reported in the abstract
Model fit of bi-factor IRT models (RMSEA)
Root mean square error of approximation (RMSEA) range, anxiety (P value range 0.0099-0.7529)
0.000-0.053
RMSEA range, depression (P value range 0.0168-0.2233)
0.033-0.061
Observational data: associations, not effects.
Original publication
Screening for anxiety and depression in clinical practice: translating scores from World Health Organization-5/Anxiety Symptom Scale-2/Major Depression Inventory-2 to Hospital Anxiety and Depression Scale. Eur J Prev Cardiol. Published 26 May 2023. doi:10.
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