Arrhythmias & electrophysiology

Secular trends in the incidence of atrial fibrillation across different ages and sexes in Taiwan from 2001 to 2021

Heart RhythmPublished retrospective study

Authors' conclusion

This study revealed complex secular trends of AF incidence in the past 21 years, with decreasing overall SIRs but increasing annual IRs in younger populations. The intricate interplay between AF incidence, age, and sex emphasizes the need for age- and sex-specific strategies in AF prevention and management. The observed relationship between comorbidity burden and AF incidence suggests differential effectiveness of cardiovascular risk management across patient subgroups.

Study context

Population
Chinese population in Taiwan, National Health Insurance Research Database, 2000 to 2021
Outcome
Total number of AF cases
Follow-up
2000 to 2021

Main finding

As reported in the abstract

Atrial fibrillation (AF) cases in 2000

24,450

AF cases in 2021

32,817

Observational data: associations, not effects.

Further findings

Standardized IR (SIR) · 2000 to 2021

SIR decreased from
170.62 per 100,000 person-years
SIR decreased to
112.38 per 100,000 person-years

Incidence rates (IRs) by sex

Male patients demonstrated higher IRs than female patients across all age groups

IRs by age

The annual IRs substantially increased with age

Trend in IRs

IRs exhibited a declining trend, except in men aged 20-49 years and women aged 20-34 years

SIR trends by comorbidity burden

Individuals with lower comorbidity burden demonstrated lower SIRs and earlier declines in SIRs

Original publication

Secular trends in the incidence of atrial fibrillation across different ages and sexes in Taiwan from 2001 to 2021. Heart Rhythm. Published 4 April 2025. doi:10.1016/j.hrthm.2025.03.2001

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