Arrhythmias & electrophysiology
Severe Periprocedural Complications After Ablation for Atrial Fibrillation: An International Collaborative Individual Patient Data Registry
Authors' conclusion
This large worldwide collaborative study highlighted that tamponade, stroke, cardiac arrest, esophageal fistula, and death are rare after AF ablation. Older age, female sex, procedure duration, a dilated left atrium, and the use of radiofrequency energy were associated with severe complications in this multinational cohort. One in 8 patients with tamponade required cardiac surgery.
Study context
- Population
- Patients undergoing catheter ablation for atrial fibrillation (AF)
- Participants
- 33,879 procedures
- Outcome
- Incidence of periprocedural severe complications
- Follow-up
- Periprocedural
Methodological details23 centres worldwide, individual patient data
- 23 centres worldwide
- Individual patient data
Main finding
As reported in the abstract
Severe complications
- Severe complications, n
- 271
- Tamponade
- 6.8‰
- Stroke
- 0.97‰
- Cardiac arrest
- 0.41‰
- Esophageal fistula
- 0.21‰
- Death
- 0.21‰
Observational data: associations, not effects.
Further findings
Predictors of composite of all severe complications
- Independently associated: age, female sex, dilated left atrium, procedure duration, radiofrequency energy
Cardiac surgery among patients with tamponade
- Required cardiac surgery
- 13%
Discharge in patients with complications
- Discharged directly home
- 93%
- Median length of stay (Q1-Q3: 3-7 days)
- 5 days
Original publication
Severe Periprocedural Complications After Ablation for Atrial Fibrillation: An International Collaborative Individual Patient Data Registry. JACC Clin Electrophysiol. Published 29 May 2024. doi:10.
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