Arrhythmias & electrophysiology
Targeting Wavefront Discontinuity Lines for Scar-Related Ventricular Tachycardia Ablation: A Novel Functional Substrate Ablation Approach
Authors' conclusion
WADLs can be automatically projected in a majority of patients in a mixed cohort of cardiomyopathy etiology, mapped wavefronts, and myocardial surfaces mapped. Targeting WADLs results in low rate of VT recurrence at 1 year.
Study context
- Population
- Mixed cohort of patients undergoing scar-related ventricular tachycardia (VT) ablation52 ablations · 71 substrate maps
- Participants
- 49 participants
- Outcome
- WADL presence, proximity of critical VT sites to WADLs, and VT recurrence / VT-free survival after WADL-targeted ablation
Methodological detailsMaps: 18.8% epicardial; 62.0% RV paced, 28.2% sinus rhythm, 9.9% LV paced, wavefront discontinuity lines (WADLs) identified using the Carto Extended Early Meets Late module
- Maps: 18.8% epicardial; 62.0% RV paced, 28.2% sinus rhythm, 9.9% LV paced
- WADLs identified using the Carto Extended Early Meets Late module
Main finding
As reported in the abstract
Maps with WADLs present
49 of 71
69.0%
Critical VT sites in close proximity (≤15 mm) to a WADL, at WADL threshold of 30%
73.9%
VT-free survival at 1 year
62%
1-year risk of VT recurrence (competing risk model)
23%
Observational data: associations, not effects.
Further findings
VT-free survival and VT recurrence · 1 year
- VT-free survival
- 62%
- Risk of VT recurrence (competing risk model)
- 23%
Original publication
Targeting Wavefront Discontinuity Lines for Scar-Related Ventricular Tachycardia Ablation: A Novel Functional Substrate Ablation Approach. JACC Clin Electrophysiol. Published 29 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →