Acute cardiac care & resuscitation

Sex differences in out-of-hospital cardiac arrest across age groups

HeartPublished Analysis of all out-of-hospital cardiac arrest (OHCA) occurring between May 2011 and December 2018 in Paris and its suburbs

Authors' conclusion

Sex differences in OHCA characteristics and outcomes were observed across all age groups and became more pronounced with increasing age, consistently indicating a better prognosis for males.

Study context

Population
Out-of-hospital cardiac arrest cases in Paris and its suburbs, May 2011 to December 2018, across three age groups: paediatric patients (28 days-18years), young adults (18–35 years) and older adults (≥35 years)OHCA cases, 6185 (33.0%) were females · paediatric patients 360 · young adults 1,240 · older adults 17,167
Participants
18,767 cases
Comparison
OHCA in females versus males
  • Femalesn = 6,185
Outcome
Survival to hospital discharge
Methodological detailslogistic regression
  • Logistic regression

Main finding

As reported in the abstract

P < 0.001

Secondary outcomes

Age, paediatric patients · males older

P = 0.029

Age, older adults · males younger

P < 0.001

No-flow time, paediatric patients · shorter in males

P = 0.007

No-flow time, young adults · shorter in females

P = 0.035

OHCA in public areas, young adults

P < 0.001

OHCA during sport, young adults

P < 0.001

Shocked, older adults

P < 0.001

Managed with amiodarone, older adults

P < 0.001

OHCA in public areas, older adults

P < 0.001

OHCA during sport, older adults

P < 0.001

OutcomeOR (95% CI)
Coronary angiographyLess often in females · After adjustment0.54 (0.46–0.64)

Original publication

Sex differences in out-of-hospital cardiac arrest across age groups. Heart. Published 6 November 2025. doi:10.1136/heartjnl-2025-326987

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.