Heart failure & cardiomyopathies
Sex Differences in the Association Between Nutritional Status and in-Hospital Mortality in Heart Failure with Preserved Ejection Fraction (HFpEF) Patients
Authors' conclusion
In male patients with HFpEF, elevated NRS2002 scores showed significantly higher odds of in-hospital mortality. Higher BMI was generally associated with lower odds of mortality, with this protective effect remaining consistent in the population sample, regardless of the NRS2002 score.
Study context
- Population
- Patients admitted with acute heart failure in whom HFpEF was identified as the underlying diagnosis, 08.2018–08.2020
- Participants
- 234 patients
- Exposure
- Associations between nutritional indices (NRS2002, body mass index (BMI)) and in-hospital mortality, with interactions by sex
- Outcome
- In-hospital mortality by NRS2002 score in male patients
Main finding
As reported in the abstract
Odds at NRS2002 = 4 (BMI = 28)
47.512
Odds at NRS2002 = 1 (BMI = 28)
0.031
Observational data: associations, not effects.
Further findings
| Outcome | OR | P value |
|---|---|---|
| In-hospital mortality by BMIPer-unit; BMI negatively modulated the odds of death | 0.843 | P = 0.012 |
- In-hospital mortality by BMI: NRS2002 did not significantly influence the BMI-mortality relationship (P = 0.289)
Association between NRS2002 and mortality in women
- No such association between NRS2002 and mortality was found in women
Original publication
Sex Differences in the Association Between Nutritional Status and in-Hospital Mortality in HFpEF Patients. ESC Heart Fail. Published 21 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →