Simplified Rapid Hydration Prevents Contrast-Associated Acute Kidney Injury Among Chronic Kidney Disease (CKD) Patients Undergoing Coronary Angiography
Primary result · CA-AKIResult — go to the resultRelative risk 0.8 95% CI 0.5–1.2Authors' conclusion
In CKD patients undergoing CAG, SH is noninferior to standard hydration in preventing CA-AKI with a shorter hydration duration.
Study context
- Population
- Patients with CKD undergoing coronary angiography
- Participants
- 1,002 patients
- Comparison
- Simplified rapid hydration vs standard hydration
- Primary endpoint
- Contrast-associated acute kidney injury (CA-AKI): ≥25% or 0.5-mg/dL rise in serum creatinine from baseline
- Follow-up
- Within 48 to 72 hours
Methodological detailsmulticentre, open-label, non-inferiority, 21 teaching hospitals
- Multicentre
- Open-label
- Non-inferiority
- 21 teaching hospitals
Primary result
CA-AKI
Relative risk
0.8
95% CI 0.5–1.2
P = 0.216
Events by treatment group
SHvs Control
RR 0.8 (95% CI 0.5–1.2); P = 0.216
As reported in the abstract
Further findings
Hydration duration
P < 0.001
Acute HF and 1-year MACE
- Did not differ significantly between groups
Original publication
Simplified Rapid Hydration Prevents Contrast-Associated Acute Kidney Injury Among CKD Patients Undergoing Coronary Angiography. JACC Cardiovasc Interv. Published 26 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →