Arrhythmias & electrophysiology

Single-lead electrocardiogram Artificial Intelligence model with risk factors detects atrial fibrillation during sinus rhythm

EuropacePublished Diagnostic accuracy study

Authors' conclusion

An AI model using a single-lead SR ECG and six risk factors can identify patients with concurrent AF with similar accuracy as a 12-lead ECG-AI model.

Study context

Population
Atrial fibrillation (AF) patients in sinus rhythm (SR) around the time of diagnosis and age- and sex-matched controls13,479 AF + 53,916 control electrocardiogram (ECGs)
Comparison
Single-lead ECG AI model with or without risk factors vs 12-lead ECG AI model
Outcome
Detection of AF from SR ECG (AUC)
Methodological detailsretrospective, age- and sex-matched controls
  • Retrospective
  • Age- and sex-matched controls

Performance

As reported in the abstract

AF detection
Test or modelAUC
Single-lead model0.74
Single-lead model + 6 risk factors0.76

AUC

Single-lead model0.74
Single-lead model + 6 risk factors0.76

Further findings

Model bias by age and sex

Results stable for both sexes, over ages 40 to 90 years

Risk factors needed

6 of 17 clinical variables sufficient for optimal accuracy

Original publication

Single-lead electrocardiogram Artificial Intelligence model with risk factors detects atrial fibrillation during sinus rhythm. Europace. Published 11 December 2023. doi:10.1093/europace/euad354

Composed by AI from the published abstract and checked against it. How Briefs are made →

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