Arrhythmias & electrophysiology

Coronary artery disease in atrial fibrillation ablation: impact on arrhythmic outcomes

EuropacePublished Prospective cohort study

Authors' conclusion

In patients undergoing CT scan before AF ablation, critical CAD was diagnosed in 7.1% of patients. Coronary artery disease and revascularization were not independent predictors of recurrence

Study context

Population
Patients with atrial fibrillation (AF) undergoing first cryoballoon catheter ablation (CA) with contrast computed tomography (CT) pre-ablation, Universitair Ziekenhuis Brussel, Belgium, 2015–2019
Participants
576 consecutive patients
Exposure
Coronary artery disease (CAD) vs no CAD on pre-ablation CT
  • Critical CADn = 41
  • CADn = 122
Outcome
Prevalence of CAD detected by cardiac CT pre-ablation; impact of CAD and revascularization on outcomes after AF ablation
Methodological detailssingle-centre, consecutive patients
  • Single-centre
  • Consecutive patients

Main finding

As reported in the abstract

Prevalence of CAD at CT

Observational data: associations, not effects.

Further findings

Atrial tachyarrhythmia (AT) recurrence: predictors · follow-up

HR
Critical CAD1.79
Persistent AFIndependent predictor (Cox multivariate)2.93
Left atrium volume indexIndependent predictor (Cox multivariate)1.04
  • Atrial tachyarrhythmia (AT) recurrence: predictors: Cox univariate only; not an independent predictor in multivariate analysis

Atrial tachyarrhythmia (AT) recurrence: predictors · follow-up

CAD and revascularization not independent predictors of recurrence

Original publication

Coronary artery disease in atrial fibrillation ablation: impact on arrhythmic outcomes. Europace. Published 8 December 2023. doi:10.1093/europace/euad328

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