Arrhythmias & electrophysiology
Smoking Cessation and Incident Atrial Fibrillation in a Longitudinal Cohort
Authors' conclusion
Compared to those who continue to smoke, smoking cessation was associated with a lower risk of AF.
Study context
- Population
- UK Biobank participants with a smoking history and without prevalent atrial fibrillation (AF) at baseline11,214 (7.6%) developed AF
- Participants
- 146,772 participants
- Exposure
- Former smokers and those who quit during the study vs current smokers
- Current smokersn = 37,377reference
- Former smokersn = 105,429
- Quit during studyn = 3,966
- Outcome
- Incident AF
- Follow-up
- Mean 12.7 ± 2.0 years
Methodological detailsUK Biobank, serial smoking assessments
- UK Biobank
- Serial smoking assessments
Main finding
As reported in the abstract
Incident AF (adjusted)
Each group vs current smokersHazard ratio (95% CI)
Former smokers13% lower adjusted risk
0.87(0.83–0.91)
Quit during study18% lower adjusted risk
0.82(0.70–0.95)
Observational data: associations, not effects.
Original publication
Smoking Cessation and Incident Atrial Fibrillation in a Longitudinal Cohort. JACC Clin Electrophysiol. Published 11 September 2024. doi:10.
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