Coronary disease & ACS

Social Determinants of Health and 30-Day Readmission After Acute Myocardial Infarction in the REGARDS Study

JACC AdvPublished cross-sectional study

Authors' conclusion

A cumulative burden of SDOHs is associated with an increased risk of readmission/ED visits after AMI hospitalization. SDOH burden may be a useful approach in identifying individuals presenting with AMI who are most vulnerable for readmission.

Study context

Population
Adults ≥65 years from the Reasons for Geographic and Racial Differences in Stroke study discharged after an acute myocardial infarction (AMI) between 2003 and 2019612 participants with validated social determinants of health (SDOH) counts
Participants
753 adults
Exposure
Associations between SDOH and risk of readmission/emergency department (ED) visit
  • 0/1 SDOHn = 273reference
  • 2 SDOHn = 117
  • 3+ SDOHn = 222
Outcome
Readmission/ED visit
Follow-up
30-day

Main finding

As reported in the abstract

Individuals with readmission/ED visit

219

29.1%

Observational data: associations, not effects.

Further findings

OutcomeRR (95% CI)
Readmission/ED visit risk by number of SDOHs, adjusted for age and region2 SDOHvs 0/1 SDOH1.15 (0.83–1.60)
Readmission/ED visit risk by number of SDOHs, adjusted for age and region3+ SDOHvs 0/1 SDOH1.56 (1.20–2.01)
Readmission/ED visit risk by number of SDOHs, fully adjusted model2 SDOHvs 0/1 SDOH1.12 (0.81–1.56)
Readmission/ED visit risk by number of SDOHs, fully adjusted model3+ SDOHvs 0/1 SDOH1.37 (1.04–1.80)
  • Readmission/ED visit risk by number of SDOHs, adjusted for age and region: P trend = 0.001
  • Readmission/ED visit risk by number of SDOHs, fully adjusted model: P trend = 0.026

Participant characteristics

Women
39.1% (295/753)
Black
27.5% (207/753)
Median age
77 years (72-82 years)

Original publication

Social Determinants of Health and 30-Day Readmission After Acute Myocardial Infarction in the REGARDS Study. JACC Adv. Published 13 February 2025. doi:10.1016/j.jacadv.2025.101584

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