Social Determinants of Health and 30-Day Readmission After Acute Myocardial Infarction in the REGARDS Study
Authors' conclusion
A cumulative burden of SDOHs is associated with an increased risk of readmission/ED visits after AMI hospitalization. SDOH burden may be a useful approach in identifying individuals presenting with AMI who are most vulnerable for readmission.
Study context
- Population
- Adults ≥65 years from the Reasons for Geographic and Racial Differences in Stroke study discharged after an acute myocardial infarction (AMI) between 2003 and 2019612 participants with validated social determinants of health (SDOH) counts
- Participants
- 753 adults
- Exposure
- Associations between SDOH and risk of readmission/emergency department (ED) visit
- 0/1 SDOHn = 273reference
- 2 SDOHn = 117
- 3+ SDOHn = 222
- Outcome
- Readmission/ED visit
- Follow-up
- 30-day
Main finding
As reported in the abstract
Individuals with readmission/ED visit
219
29.1%
Observational data: associations, not effects.
Further findings
| Outcome | RR (95% CI) | |
|---|---|---|
| Readmission/ED visit risk by number of SDOHs, adjusted for age and region2 SDOHvs 0/1 SDOH | 1.15 (0.83–1.60) | |
| Readmission/ED visit risk by number of SDOHs, adjusted for age and region3+ SDOHvs 0/1 SDOH | 1.56 (1.20–2.01) | |
| Readmission/ED visit risk by number of SDOHs, fully adjusted model2 SDOHvs 0/1 SDOH | 1.12 (0.81–1.56) | |
| Readmission/ED visit risk by number of SDOHs, fully adjusted model3+ SDOHvs 0/1 SDOH | 1.37 (1.04–1.80) | |
| 0.512Relative risk (log scale) |
- Readmission/ED visit risk by number of SDOHs, adjusted for age and region: P trend = 0.001
- Readmission/ED visit risk by number of SDOHs, fully adjusted model: P trend = 0.026
Participant characteristics
- Women
- 39.1% (295/753)
- Black
- 27.5% (207/753)
- Median age
- 77 years (72-82 years)
Original publication
Social Determinants of Health and 30-Day Readmission After Acute Myocardial Infarction in the REGARDS Study. JACC Adv. Published 13 February 2025. doi:10. 1016/ j. jacadv. 2025. 101584
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