Heart failure & cardiomyopathies
Socio-Economic Inequalities and Heart Failure Morbidity and Mortality: A Systematic Review and Data Synthesis
Authors' conclusion
This systematic review, using contemporary data, shows that while socio-economic disparity may influence HF incidence, management and subsequent adverse events, these associations are not uniformly predictive.
Study context
- Population
- Observational studies of socio-economic status (SES) (individual and area level, single and composite indicators) and heart failure (HF) outcomes79 studies + 5 via cross-referencing
- Comparison
- Low vs higher SES
- Outcome
- HF incidence and prevalence, HF hospitalizations, WHF, all-cause mortality and treatment (medical, device, advanced HF therapies)
Methodological detailsPRISMA, six databases, 4124 studies screened
- PRISMA
- Six databases
- 4124 studies screened
Pooled result
As reported in the abstract
Proportion of studies showing low SES associated with worse outcome
- Low SES associated with increased HF incidence
- 72%
- Low SES associated with increased HF prevalence
- 75%
- Low SES associated with increased mortality
- 45%
- Mortality: mixed results (indicator, gender or follow-up)
- 18%
- Mortality: non-significant results
- 38%
Further pooled results
Worsening HF (WHF), medical therapy prescriptions, use of devices and advanced HF therapies
- Similar patterns to mortality
- No clear pattern in SES indicators used and HF outcomes
Original publication
Socio-Economic Inequalities and Heart Failure Morbidity and Mortality: A Systematic Review and Data Synthesis. ESC Heart Fail. Published 25 September 2024. doi:10.
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