Arrhythmias & electrophysiologyCohort study
Spatial dissociation between atrial exit and the putative slow pathway substrate in atypical atrioventricular nodal reentrant tachycardia (AVNRT)
- Case series
Authors' conclusion
In atypical AVNRT, atrial exits were frequently spatially dissociated from a putative slow pathway substrate identified during sinus rhythm. These findings provide hypothesis-generating mechanistic insight and suggest that sinus rhythm high-PF mapping may represent a feasible substrate-oriented approach warranting validation in larger controlled studies.
Study context
- Population
- Patients with atypical AVNRT undergoing catheter ablation guided by PF mapping during sinus rhythmpatients with atypical AVNRT · fast-slow 8 · slow-slow 3
- Participants
- 11 patients
Main finding
As reported in the abstract
- High-PF sites identified in all patients, most commonly near the 5-o'clock tricuspid annular position
Observational data: associations, not effects.
Further findings
Spatial concordance between high-PF and atrial earliest activation sites
- mean distance
- 10.9 ± 4.1 mm
- No patient demonstrated spatial concordance
Elimination of retrograde slow pathway conduction by ablation at the high-PF region alone
- patients
- 9 of 11 patients (82%)
Additional atrial exit ablation required
- patients
- 2 patients
Acute success and recurrence · 6 months
- Acute success achieved in all patients
- No recurrences
Original publication
Summarised from the published abstract; every number is checked against it