Coronary disease & ACS

Strategy Selection and Outcomes of Tip-Detection in CTO-PCI: Intraplaque Tracking vs Antegrade Dissection and Re-Entry

JACC AdvPublished retrospectively analyzed

Authors' conclusion

TD-primary ADR was preferentially selected for complex, calcified CTOs. Procedural efficiency appeared driven mainly by lesion characteristics rather than the initial TD strategy, supporting individualized TD strategy selection based on lesion morphology and technical feasibility.

Study context

Population
Tip-detection (TD)-attempted chronic total occlusion (CTO)-percutaneous coronary intervention cases from November 2020 to December 2023TD-attempted CTO-PCI cases, secondary metrics in 69 successful cases · TD-primary IPT 37 · TD-primary ADR 36
Participants
73 cases
Comparison
TD-primary IPT vs TD-primary ADR
  • TD-primary IPTn = 37
  • TD-primary ADRn = 36

Main finding

As reported in the abstract

TD success

Further findings

Selection for J-CTO score ≥2

Selection for severe calcification

Lesion crossing time (successful cases) · shorter with TD-primary IPT

Stent length (successful cases) · shorter with TD-primary ADR

OutcomeTD-primary IPTTD-primary ADR
Final procedural success94.6% (95% CI 81.8%–99.3%)97.2% (95% CI 85.5%–99.9%)
  • Selection for J-CTO score ≥2: P = 0.043
  • Selection for severe calcification: P < 0.001
  • Lesion crossing time (successful cases): P = 0.046
  • Stent length (successful cases): P = 0.041

Multivariable models

Severe calcification was associated with longer lesion crossing time
Bending ≥45° was associated with longer stent length

Original publication

Strategy Selection and Outcomes of Tip-Detection in CTO-PCI: Intraplaque Tracking vs Antegrade Dissection and Re-Entry. JACC Adv. Published 22 September 2026. doi:10.1016/j.jacadv.2026.103274

Summarised from the published abstract; every number is checked against it

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