Arrhythmias & electrophysiology
Strength-Based Exercise Is Not Associated With Ventricular Arrhythmia in Arrhythmogenic Cardiomyopathy—Towards Safer Exercise Options
Authors' conclusion
Our study found no association between strength exercise and risk of sustained VA. These findings support individualized risk stratification and shared decision-making in ACM care and show the need for additional studies to guide recommendations.
Study context
- Population
- Individuals with arrhythmogenic cardiomyopathy (ACM) and/or P/LP ACM gene variants exposed to strength-based exerciseindividuals enrolled, median age 34 years
- Participants
- 355 individuals
- Exposure
- Endurance vs strength exercise on ventricular arrhythmia (VA) risk
- Outcome
- Distribution of exercise groups
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
Overall lifetime risk of VA
- Higher with increased aerobic exercise (dual + endurance) than without (strength + sedentary)
- No difference between dual vs endurance athletes, nor strength athletes vs sedentary
VA (multivariable Cox regression)
- No association of VA with strength training, whereas risk of endurance exercise was significant
- Multivariable
Original publication
Strength-Based Exercise Is Not Associated With Ventricular Arrhythmia in Arrhythmogenic Cardiomyopathy—Towards Safer Exercise Options. JACC Clin Electrophysiol. Published 29 August 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →