Heart failure & cardiomyopathies
Stroke in Individuals With Hypertrophic Cardiomyopathy and Sleep Apnea
Authors' conclusion
Subjects with HCM and SAS are at risk for stroke.
Study context
- Population
- Adult inpatients with hypertrophic cardiomyopathy (HCM) and sleep apnea syndrome (aged >21 years), US National Inpatient Sample 2010–2019
- Participants
- 13,581 inpatients
- Outcome
- Stroke and factors associated with stroke
Methodological detailsNational Inpatient Sample 2010-2019, multivariable logistic regression
- National Inpatient Sample 2010-2019
- Multivariable logistic regression
Main finding
As reported in the abstract
Stroke
- Prevalence of stroke
- 3.3%
- Female (positive association)
- OR: 1.30
- Hypertension (positive association)
- OR: 1.48
- Ischemic heart disease (positive association)
- OR: 1.37
- Dyslipidemia (positive association)
- OR: 1.55
- Peripheral vascular disease (positive association)
- OR: 2.17
- Urinary tract infections (positive association)
- OR: 1.53
- Age 21 to 50 years (negative association)
- OR: 0.722
- Obesity (negative association)
- OR: 0.69
- Chronic HF (negative association)
- OR: 0.79
- Anticoagulant use (negative association)
- OR: 0.76
Observational data: associations, not effects.
Original publication
Stroke in Individuals With Hypertrophic Cardiomyopathy and Sleep Apnea. JACC Adv. Published 23 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →