Heart failure & cardiomyopathies
SUBCUT heart failure (HF) II: rationale and design of a multicentre randomized controlled trial of SUBCUTaneous furosemide to support early discharge in patients admitted to hospital due to Heart Failure
Study context
- Population
- Patients with HF receiving inpatient treatment with IV loop diuretic168 randomised as of October 2025
- Participants
- 170 patients
- Planned comparison
- Early supported discharge with subcutaneous furosemide via wearable pump vs continued inpatient IV furosemide
- Primary endpoint
- Days alive and out of hospital
- Follow-up
- 30 days
Methodological detailsrationale and design, multicentre, active comparator, 20 UK hospitals
- Rationale and design
- Multicentre
- Active comparator
- 20 UK hospitals
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
SUBCUT HF II: rationale and design of a multicentre randomized controlled trial of SUBCUTaneous furosemide to support early discharge in patients admitted to hospital due to Heart Failure. Eur J Heart Fail. Published 12 January 2026. doi:10. 1093/ ejhf/ xuaf018
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