Heart failure & cardiomyopathies

SUBCUT heart failure (HF) II: rationale and design of a multicentre randomized controlled trial of SUBCUTaneous furosemide to support early discharge in patients admitted to hospital due to Heart Failure

Eur J Heart FailPublished Randomised controlled trial

Study context

Population
Patients with HF receiving inpatient treatment with IV loop diuretic168 randomised as of October 2025
Participants
170 patients
Planned comparison
Early supported discharge with subcutaneous furosemide via wearable pump vs continued inpatient IV furosemide
Primary endpoint
Days alive and out of hospital
Follow-up
30 days
Methodological detailsrationale and design, multicentre, active comparator, 20 UK hospitals
  • Rationale and design
  • Multicentre
  • Active comparator
  • 20 UK hospitals

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

SUBCUT HF II: rationale and design of a multicentre randomized controlled trial of SUBCUTaneous furosemide to support early discharge in patients admitted to hospital due to Heart Failure. Eur J Heart Fail. Published 12 January 2026. doi:10.1093/ejhf/xuaf018

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