Acute cardiac care & resuscitation

Sudden cardiac arrest in patients with cancer in the general population: insights from the Paris-SDEC registry

HeartPublished Prospective population-based registry study

Authors' conclusion

One in 20 SCA occurs in patients with a history of cancer, yet with fewer cardiac causes than in patients who are cancer-free. Still, in-hospital outcomes remain similar even in patients with known cancer.

Study context

Population
Adults with out-of-hospital sudden cardiac arrest (SCA) admitted alive in hospital, Paris and suburbs, 2011–2019207 (5.1%) with cancer
Participants
4,069 adults
Exposure
Patients with cancer vs patients without cancer
  • Cancern = 207
Outcome
In-hospital survival after SCA

Main finding

As reported in the abstract

In-hospital survival

P = 0.27

Observational data: associations, not effects.

Further findings

Non-shockable rhythm

P < 0.001

Baseline characteristics: age, women, underlying CVD · age 69.2 vs 59.3 years
P < 0.001
Baseline characteristics: age, women, underlying CVD · women 37.2% vs 28.0%
P = 0.006
Baseline characteristics: age, women, underlying CVD · underlying CVD 41.1% vs 32.5%
P = 0.01
Cause of SCA: cardiac (mostly ACS) and respiratory (PE and hypoxaemia) · cardiac causes 25.5% vs 46.8%
P < 0.001
Cause of SCA: cardiac (mostly ACS) and respiratory (PE and hypoxaemia) · respiratory causes 34.2% vs 10.8%
P < 0.001

Non-shockable rhythm

No significant difference in witness presence and cardiopulmonary resuscitation (CPR) performed

Predictors of in-hospital survival in the cancer group

Public location, CPR by witness and shockable rhythm were independent predictors of in-hospital survival

Original publication

Sudden cardiac arrest in patients with cancer in the general population: insights from the Paris-SDEC registry. Heart. Published 2 July 2024. doi:10.1136/heartjnl-2024-324137

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