Acute cardiac care & resuscitation

Survival in relation to number of defibrillation attempts in out-of-hospital cardiac arrest

ResuscitationPublished Retrospective cohort study

Authors' conclusion

In this registry-based retrospective cohort study, additional defibrillations were associated with a lower survival. This association persisted after adjustments for patient and resuscitation characteristics.

Study context

Population
Adults (≥18 y) with out-of-hospital cardiac arrest (OHCA) and initial shockable rhythm, Sweden, 2010–2020
Participants
10,549 adults
Exposure
Number of defibrillations
  • One shockn = 3,006
  • Two shocksn = 1,665
  • Three shocksn = 1,336
  • Four shocksn = 1,064
  • Five or more shocksn = 3,478
Outcome
Survival to 30 days
Follow-up
30 days
Methodological detailsregistry-based
  • Registry-based

Main finding

As reported in the abstract

30-day survival (adjusted probability), by number of defibrillations

Adjusted probability of survival, one defibrillation

42%

Adjusted probability of survival, two defibrillations

36%

Adjusted probability of survival, three defibrillations

30%

Adjusted probability of survival, four defibrillations

25%

Observational data: associations, not effects.

Original publication

Survival in relation to number of defibrillation attempts in out-of-hospital cardiac arrest. Resuscitation. Published 15 November 2024. doi:10.1016/j.resuscitation.2024.110435

Summarised from the published abstract; every number is checked against it

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