Acute cardiac care & resuscitation
Survival in relation to number of defibrillation attempts in out-of-hospital cardiac arrest
Authors' conclusion
In this registry-based retrospective cohort study, additional defibrillations were associated with a lower survival. This association persisted after adjustments for patient and resuscitation characteristics.
Study context
- Population
- Adults (≥18 y) with out-of-hospital cardiac arrest (OHCA) and initial shockable rhythm, Sweden, 2010–2020
- Participants
- 10,549 adults
- Exposure
- Number of defibrillations
- One shockn = 3,006
- Two shocksn = 1,665
- Three shocksn = 1,336
- Four shocksn = 1,064
- Five or more shocksn = 3,478
- Outcome
- Survival to 30 days
- Follow-up
- 30 days
Methodological detailsregistry-based
- Registry-based
Main finding
As reported in the abstract
30-day survival (adjusted probability), by number of defibrillations
Adjusted probability of survival, one defibrillation
42%
Adjusted probability of survival, two defibrillations
36%
Adjusted probability of survival, three defibrillations
30%
Adjusted probability of survival, four defibrillations
25%
Observational data: associations, not effects.
Original publication
Survival in relation to number of defibrillation attempts in out-of-hospital cardiac arrest. Resuscitation. Published 15 November 2024. doi:10. 1016/ j. resuscitation. 2024. 110435
Summarised from the published abstract; every number is checked against it