Arrhythmias & electrophysiology

Tailored electrocardiographic-based criteria for different pacing locations within the left bundle branch

Heart RhythmPublished Diagnostic accuracy study

Authors' conclusion

Tailored ECG-based criteria might be useful to confirm LBBP at different pacing locations within the LBB.

Study context

Population
Consecutive patients with confirmed left bundle branch pacing (LBBP)unequivocal left bundle branch (LBB) capture
Participants
147 patients
Comparison
Electrocardiographic (ECG)-based criteria for LBBP across pacing locations within the LBB
Outcome
Diagnostic performance and 100%-specific cutoffs of V6-RWPT, V6-V1 interpeak interval and aVL-RWPT for LBBP at each pacing location
Methodological detailsconsecutive patients
  • Consecutive patients

Performance

As reported in the abstract

Cutoff values with 100% specificity for LBBP discrimination
Test or modelV6-RWPT cutoffV6-V1 interpeak interval cutoffaVL-RWPT cutoff
Left bundle trunk pacing (LBTP)75 ms35.5 ms74 ms
Left septal fascicular pacing (LSFP)79.5 ms46 ms74.5 ms
Left posterior fascicular pacing (LPFP)68 ms53.5 ms73.5 ms
Left anterior fascicular pacing (LAFP)81 ms41 ms68 ms

V6-RWPT cutoff

Left bundle trunk pacing (LBTP)75 ms
Left septal fascicular pacing (LSFP)79.5 ms
Left posterior fascicular pacing (LPFP)68 ms
Left anterior fascicular pacing (LAFP)81 ms

V6-V1 interpeak interval cutoff

Left bundle trunk pacing (LBTP)35.5 ms
Left septal fascicular pacing (LSFP)46 ms
Left posterior fascicular pacing (LPFP)53.5 ms
Left anterior fascicular pacing (LAFP)41 ms

aVL-RWPT cutoff

Left bundle trunk pacing (LBTP)74 ms
Left septal fascicular pacing (LSFP)74.5 ms
Left posterior fascicular pacing (LPFP)73.5 ms
Left anterior fascicular pacing (LAFP)68 ms

Further findings

Pacing location achieved

Left fascicular pacing
82.8%
LBTP
17.2%

Original publication

Tailored electrocardiographic-based criteria for different pacing locations within the left bundle branch. Heart Rhythm. Published 21 September 2023. doi:10.1016/j.hrthm.2023.09.015

Summarised from the published abstract; every number is checked against it

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