Arrhythmias & electrophysiology
Targetable atrial tachycardias after artificial intelligence–guided ablation of persistent atrial fibrillation
Authors' conclusion
Most ATs observed after artificial intelligence-guided, dispersion-based catheter ablation are targetable. The prevalence of these ATs and the repeat procedure rate are reduced when strategic completion of dispersion-based ablation was obtained.
Study context
- Population
- Patients with persistent atrial fibrillation (AF) with post-AF atrial tachycardia (ATs) during AI-guided, dispersion-based ablation in the TAILORED-AF trial
- Participants
- 96 patients · 140 ATs
- Comparison
- Complete vs incomplete ablation set in common macroreentry AT regions
- Primary endpoint
- Mechanism and locations of ATs; adherence to protocol-recommended ablation and its relation to ATs
Methodological detailspost hoc analysis
- Post hoc analysis
Primary result
As reported in the abstract
AT mechanisms during index procedure
Macroreentrant ATs (29% perimitral, 42% peritricuspid, 20% roof dependent, 9% other)
76
Localized ATs
37
ATs with undetermined mechanisms
12
Unstable ATs
15
Further findings
| Outcome | Complete ablation set | Incomplete ablation set | OR (95% CI) | P value | |
|---|---|---|---|---|---|
| Repeat ablations | 22% | 48% | 0.31 (0.12–0.79) | P = 0.02 | |
| 0.10.31310Odds ratio (log scale) |
Original publication
Targetable atrial tachycardias after artificial intelligence–guided ablation of persistent atrial fibrillation. Heart Rhythm. Published 14 November 2025. doi:10.
Summarised from the published abstract; every number is checked against it