Valvular & structural heart disease
A systematic algorithm for large-bore arterial access closure after transcatheter aortic valve implantation (TAVI): the TAVI-MultiCLOSE study
Authors' conclusion
Use of the MultiCLOSE vascular closure algorithm was demonstrated to contribute to an easy, safe, efficacious and durable vascular closure after TF-TAVI, resulting in a major vascular complication rate of less than 1%.
Study context
- Population
- Consecutive patients undergoing transfemoral TAVI with percutaneous large-bore arterial access closure
- Participants
- 630 patients
- Outcome
- Safety and efficacy of large-bore arterial access closure
Methodological detailsmulticentre, consecutive patients, single-group
- Multicentre
- Consecutive patients
- Single-group
Main finding
As reported in the abstract
| Group | Complete arterial haemostasis | VCD failure | Minor vascular complication | Major vascular complication |
|---|---|---|---|---|
| MultiCLOSE | 616 (98%) | 14 (2%) | 2.2% | 0.6% |
MultiCLOSE
Complete arterial haemostasis616 (98%)
VCD failure14 (2%)
Minor vascular complication2.2%
Major vascular complication0.6%
Observational data: associations, not effects.
Further findings
New minor vascular complication · 30 days
- Only one new minor vascular complication at 30 days
- 0.2%
All-cause mortality
- In-hospital all-cause mortality
- 0.2%
- 30-day all-cause mortality
- 1.0%
Original publication
A systematic algorithm for large-bore arterial access closure after TAVI: the TAVI-MultiCLOSE study. EuroIntervention. Published 18 March 2024. doi:10.
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