Heart failure & cardiomyopathies
The Association Between Office, Video, and Telemanagement Encounters and Guideline-directed Medical Therapy (GDMT) Optimization in Advanced Heart Failure with Reduced Ejection Fraction (HFrEF)
Authors' conclusion
Increased telemanagement frequency was consistently associated with faster GDMT optimization in HFrEF.
Study context
- Population
- Adults with advanced HFrEF managed in a team-based care model, University of Michigan, July 2021 to October 2024
- Participants
- 1,331 adults
- Exposure
- Low vs medium vs high frequency (tertiles) of office, video and telemanagement encounters
- Outcome
- Time to GDMT optimization (medication optimization score = 100%)
Main finding
As reported in the abstract
Time to GDMT optimization, by telemanagement frequency (unweighted model A)
Each group vs lowHazard ratio (95% CI)
Medium
1.46(1.14–1.87)
High
1.97(1.51–2.57)
Observational data: associations, not effects.
Further findings
| Outcome | HR (95% CI) | |
|---|---|---|
| Time to GDMT optimization, by telemanagement frequency (weighted Cox model)Mediumvs LowTelemanagement, weighted | 2.06 (1.51–2.80) | |
| Time to GDMT optimization, by telemanagement frequency (weighted Cox model)Highvs LowTelemanagement, weighted | 2.73 (1.97–3.79) | |
| 0.20.5125Hazard ratio (log scale) |
Time to GDMT optimization, by telemanagement frequency (weighted Cox model)
- High frequency of office encounters associated with GDMT optimization (weighted model)
Original publication
The Association Between Office, Video, and Telemanagement Encounters and GDMT Optimization in Advanced HFrEF. JACC Adv. Published 25 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →