Heart failure & cardiomyopathies

Association between visit frequency, continuity of care, and pharmacy fill adherence in heart failure patients

Am Heart JPublished Cross-sectional study

Main finding · GDMT adherenceResult — go to the resultOdds ratio 1.26 95% CI 1.03–1.53

Authors' conclusion

Continuity of care was not associated with GDMT adherence among patients with HFrEF but lower continuity of care was associated with increased all-cause and HF-hospitalizations.

Study context

Population
Adults with HF and EF ≤40%, ≥2 outpatient encounters 2017–2021, prescribed ≥1 guideline-directed medical therapies (GDMT) (beta blocker, ACEi/ARB/ARNI, MRA, SGLT2 inhibitor)
Participants
3,971 adults
Exposure
Continuity of care quantiles
Outcome
GDMT adherence (average proportion of days covered ≥80%)
Follow-up
1 year

Main finding

GDMT adherence

Odds ratio

1.26

95% CI 1.03–1.53

P = 0.024

Third COC quartilevs Highest COC quartile
OR 1.26 (95% CI 1.03–1.53); P = 0.024

As reported in the abstract

Usual Provider of Care (UPC) tertile not associated with adherence
all P > .05

Observational data: associations, not effects.

Secondary outcomes

OutcomeOR (95% CI)
All-cause hospitalization, lowest vs highest UPC and COC quantiles · 1 yearLowest quantilevs Highest quantileUPC · adjusted analyses1.53 (1.23–1.91)
All-cause hospitalization, lowest vs highest UPC and COC quantiles · 1 yearLowest quantilevs Highest quantileCOC · adjusted analyses2.54 (1.94–3.34)
HF hospitalization, lowest vs highest UPC and COC quantiles · 1 yearLowest quantilevs Highest quantileUPC · adjusted analyses1.81 (1.23–2.67)
HF hospitalization, lowest vs highest UPC and COC quantiles · 1 yearLowest quantilevs Highest quantileCOC · adjusted analyses1.77 (1.09–2.95)

Original publication

Association between visit frequency, continuity of care, and pharmacy fill adherence in heart failure patients. Am Heart J. Published 14 April 2024. doi:10.1016/j.ahj.2024.04.003

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