Cardio-oncology & other

The Association of Social Vulnerability With Maternal and Fetal Outcomes in a Cardio-Obstetrics Cohort

JACC AdvPublished cross-sectional study

Authors' conclusion

The cardio-obstetric referral population exhibited a high overall SVI. Higher social vulnerability was associated with delayed access to care but not independently associated with most adverse maternal and fetal pregnancy outcomes.

Study context

Population
Patients referred to a cardio-obstetrics programindividuals included
Participants
489 patients
Exposure
Risk of maternal and fetal outcomes by Social Vulnerability Index (SVI)
Outcome
Overall median SVI of the referral cohort
Methodological detailsall consecutive patients referred to our cardio-obstetrics program from March 2023 to January 2025
  • All consecutive patients referred to our cardio-obstetrics program from March 2023 to January 2025

Main finding

As reported in the abstract

Overall median SVI

0.833

Observational data: associations, not effects.

Further findings

Characteristics associated with increasing SVI

Increasing SVI was associated with younger age, higher BMI, Black race, and Medicaid insurance

Mean SVI by late entry to cardio-obstetrical care, neonatal intensive care unit admission, and fetal demise

Mean SVI higher with late entry to cardio-obstetrical care
P = 0.03
Mean SVI higher with neonatal intensive care unit admission
P = 0.04
Mean SVI higher with fetal demise
P < 0.001

Delayed cardio-obstetrical care

Delayed cardio-obstetrical care was associated with high SVI
  • Unadjusted regression analyses

Maternal and fetal outcomes

SVI was not independently associated with most maternal and fetal outcomes
  • Multivariable adjusted analyses

Discriminatory performance of SVI for fetal/neonatal demise

Area under the curve
0.80; 95% CI: 0.68-0.92
  • Discriminatory performance of SVI was highest for fetal/neonatal demise

Original publication

The Association of Social Vulnerability With Maternal and Fetal Outcomes in a Cardio-Obstetrics Cohort. JACC Adv. Published 27 August 2026. doi:10.1016/j.jacadv.2026.103188

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