Coronary disease & ACS

The coronary microvascular angina cardiovascular magnetic resonance imaging trial: Rationale and design

Am Heart JPublished Trial protocol (rationale and design): diagnostic study with nested randomised controlled trial

Study context

Population
Patients with angina with no obstructive coronary arteries (ANOCA) after clinically indicated invasive coronary angiography for suspected CAD, 3 UK centres
Planned comparison
Intervention vs Control
Primary endpoint
Diagnostic study: between-group difference in reclassification rate of initial (angiography-based) vs final diagnosis after CMR; RCT: mean within-subject change in Seattle Angina Questionnaire summary score (SAQSS)
Follow-up
6 months (RCT)
Methodological detailsdouble-blind, 3 regional UK centres
  • Double-blind
  • 3 regional UK centres

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

The coronary microvascular angina cardiovascular magnetic resonance imaging trial: Rationale and design. Am Heart J. Published 30 August 2023. doi:10.1016/j.ahj.2023.08.067

Summarised from the published abstract; every number is checked against it

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