Arrhythmias & electrophysiology
The functional substrate in patients with atrial fibrillation is predictive of recurrences after catheter ablation
Main finding · AF recurrence after PV ablationResult — go to the resultHazard ratio 2.539 CI 1.458–4.420Authors' conclusion
Dual high-density mapping (during sinus and paced rhythms) is able to unmask functional, rhythm-dependent phenomena that are predictive of AF recurrences during follow-up.
Study context
- Population
- Consecutive patients with atrial fibrillation (AF) referred for catheter ablation
- Participants
- 63 patients
- Outcome
- AF recurrence after catheter ablation, by functional rhythm-dependent conduction abnormalities
Methodological detailsconsecutive patients, high-density substrate mapping
- Consecutive patients
- High-density substrate mapping
Main finding
AF recurrence after PV ablation
Hazard ratio
2.539
CI 1.458–4.420
P = 0.001
Number of residual functional phenomena
HR 2.539 (CI 1.458–4.420); P = 0.001
As reported in the abstract
Observational data: associations, not effects.
Further findings
Anatomic site of functional phenomena
- Most frequent: anterior wall, then posterior wall, in sinus rhythm; pulmonary venous antra in paced rhythm
Original publication
The functional substrate in patients with atrial fibrillation is predictive of recurrences after catheter ablation. Heart Rhythm. Published 13 September 2024. doi:10. 1016/ j. hrthm. 2024. 09. 017
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