Arrhythmias & electrophysiology

The functional substrate in patients with atrial fibrillation is predictive of recurrences after catheter ablation

Heart RhythmPublished Prospective cohort study

Main finding · AF recurrence after PV ablationResult — go to the resultHazard ratio 2.539 CI 1.458–4.420

Authors' conclusion

Dual high-density mapping (during sinus and paced rhythms) is able to unmask functional, rhythm-dependent phenomena that are predictive of AF recurrences during follow-up.

Study context

Population
Consecutive patients with atrial fibrillation (AF) referred for catheter ablation
Participants
63 patients
Outcome
AF recurrence after catheter ablation, by functional rhythm-dependent conduction abnormalities
Methodological detailsconsecutive patients, high-density substrate mapping
  • Consecutive patients
  • High-density substrate mapping

Main finding

AF recurrence after PV ablation

Hazard ratio

2.539

CI 1.458–4.420

P = 0.001

Number of residual functional phenomena
HR 2.539 (CI 1.458–4.420); P = 0.001

As reported in the abstract

Observational data: associations, not effects.

Further findings

Anatomic site of functional phenomena

Most frequent: anterior wall, then posterior wall, in sinus rhythm; pulmonary venous antra in paced rhythm

Original publication

The functional substrate in patients with atrial fibrillation is predictive of recurrences after catheter ablation. Heart Rhythm. Published 13 September 2024. doi:10.1016/j.hrthm.2024.09.017

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.