Arrhythmias & electrophysiology
Enhancing origin prediction: deep learning model for diagnosing premature ventricular contractions with dual-rhythm analysis focused on cardiac rotation
Authors' conclusion
Our deep learning-based model, incorporating both PVC and SR morphologies, resulted in a higher prediction accuracy for PVC origin, considering SR is particularly important for predicting right-sided origin in patients with counterclockwise rotation.
Study context
- Population
- Patients with inferior axis premature ventricular contractions (PVCs), 11 centres (Japan, Germany; Belgium external validation)100 external validation
- Participants
- 593 patients
- Comparison
- Dual-rhythm model vs PVC model
- Outcome
- Prediction of PVC origin (right vs left side) on 12-lead ECG
Methodological detailsmulticentre, external validation, Hybrid Resnet50-based CNN and transformer model
- Multicentre
- External validation
- Hybrid Resnet50-based CNN and transformer model
Performance
As reported in the abstract
PVC origin prediction, external validation data set
| Test or model | AUC | Specificity | Accuracy | Precision | F1-score |
|---|---|---|---|---|---|
| Dual-rhythm model | 0.91 | 0.87 | 0.84 | 0.73 | 0.77 |
| PVC model | 0.86 | 0.68 | 0.74 | 0.55 | 0.68 |
AUC
Dual-rhythm model0.91
PVC model0.86
Specificity
Dual-rhythm model0.87
PVC model0.68
Accuracy
Dual-rhythm model0.84
PVC model0.74
Precision
Dual-rhythm model0.73
PVC model0.55
F1-score
Dual-rhythm model0.77
PVC model0.68
- Dual-rhythm model vs PVC model: P < 0.01 — accuracy
- Dual-rhythm model vs PVC model: P < 0.01 — precision
- Dual-rhythm model vs PVC model: P < 0.01 — specificity
- Dual-rhythm model vs PVC model: P = 0.03 — AUC
- Dual-rhythm model vs PVC model: P = 0.03 — F1-score
Further findings
Contribution to PVC origin prediction
- PVC contribution
- 77.3%
- Sinus rhythm (SR) contribution
- 22.7%
- In counterclockwise rotation, SR had greater contribution in predicting right-sided PVC origin
Original publication
Enhancing origin prediction: deep learning model for diagnosing premature ventricular contractions with dual-rhythm analysis focused on cardiac rotation. Europace. Published 13 September 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →