Heart failure & cardiomyopathies

The Global, Regional, and National Burden of Myocarditis in 204 Countries and Territories, 1990–2021: Results From the Global Burden of Disease Study 2021

Eur J Heart FailPublished Analysis of the Global Burden of Disease Study 2021

Authors' conclusion

Although the ASRs of incidence, deaths, and DALYs significantly decreased from 1990 to 2021, the global number of incidences, deaths, and DALYs increased substantially. Certain populations, including males, children, the elderly, and regions with advanced sociodemographic levels, experienced a heavier burden of myocarditis.

Study context

Population
General population, global, 1990–2021
Outcome
Burden of myocarditis: incidence, deaths and DALYs with age-standardized rates (ASRs) per 100 000 population
Follow-up
1990–2021
Methodological detailsglobal, regional and national analyses, sub-analyses by age group, sex and SDI
  • Global, regional and national analyses
  • Sub-analyses by age group, sex and SDI

Main finding

As reported in the abstract

Global burden of myocarditis · 2021
Incident cases, 2021
1.3 million (95% UI 1.1 to 1.6)
Deaths, 2021
31.7 thousand (95% UI 25.5 to 37.1)
DALY cases, 2021
96.3 thousand (95% UI 79.6 to 114.8)
Percentage change in ASR of incidence, 1990–2021
−3.9% (95% UI −4.7% to −2.9%)
Percentage change in ASR of death, 1990–2021
−28.2% (95% UI −42.2% to −12.5%)
Percentage change in ASR of DALYs, 1990–2021
−37.8% (95% UI −50.5% to −24.3%)

Further findings

Burden by sex, age and SDI

Global burden higher in males, children and the elderly
High SDI regions had the highest ASR of incidence
High-middle SDI regions had the highest age-standardized rates (ASRs) of deaths and DALYs

Original publication

The Global, Regional, and National Burden of Myocarditis in 204 Countries and Territories, 1990–2021: Results From the Global Burden of Disease Study 2021. Eur J Heart Fail. Published 22 October 2024. doi:10.1002/ejhf.3483

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