Arrhythmias & electrophysiology

The HONEST Cohort Study: Rationale and Design of a Nationwide Subcutaneous Implantable Cardioverter-Defibrillator Cohort

JACC AdvPublication date not resolvedFrench nationwide, single-arm, observational ongoing study

Study context

Population
All patients who underwent implantation of an subcutaneous implantable cardioverter-defibrillator (S-ICD) (EMBLEM, Boston Scientific) in France between October 2012 and December 201977% males, 49.9 years, 98.2% of all S-ICD implantations during the study period in France
Participants
4,924 patients
Methodological detailsClinical endpoints are centrally adjudicated
  • Clinical endpoints are centrally adjudicated

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

The HONEST Cohort Study: Rationale and Design of a Nationwide Subcutaneous Implantable Cardioverter-Defibrillator Cohort. JACC Adv. doi:10.1016/j.jacadv.2026.102604

Summarised from the published abstract; every number is checked against it

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