Acute cardiac care & resuscitation
The impact of alternate defibrillation strategies on time in ventricular fibrillation
Authors' conclusion
DSED and VC reduced VF duration and increased the likelihood of ROSC and survival compared to standard shocks. These findings may contribute to the improved survival noted in the trial.
Study context
- Population
- Patients with out-of-hospital cardiac arrest and refractory VF enrolled in the Double Sequential External Defibrillation for Refractory VF RCT1,842 shocks analyzed, 834 after three failed standard shocks
- Participants
- 342 patients
- Comparison
- VC and double sequential external defibrillation (DSED) compared to standard shocks
- DSEDn = 187
- VCn = 218
- Standardn = 429
Primary result
As reported in the abstract
Median VF time
Further findings
Proportion of shocks leading to ROSC and survival to hospital discharge · ROSC, higher with VC
P < 0.002
ROSC
P < 0.001
Survival
P = 0.002
| Outcome | DSED | VC | Standard | P value |
|---|---|---|---|---|
| Proportion of shocks leading to ROSC and survival to hospital dischargeSurvival, higher with VC | P = 0.049 | |||
| Proportion of shocks in which VF was not terminatedDSED vs standard · significantly lower with DSED | 29.9% | — not stated in the abstract | 40.6% | P = 0.013 |
— not stated in the abstract
Original publication
The impact of alternate defibrillation strategies on time in ventricular fibrillation. Resuscitation. Published 17 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →