Arrhythmias & electrophysiology

The Olive Strategy: Improved Pulmonary Vein Isolation Durability With the Pentaspline Pulsed Field Catheter

JACC Clin ElectrophysiolPublished initial clinical experience of a novel ablation protocol

Authors' conclusion

The authors report on the initial clinical experience of a novel ablation protocol for PVI with the pentaspline PFA catheter. The Olive Strategy is safe to use and significantly improves PVI durability.

Study context

Population
Patients undergoing pulmonary vein isolation (PVI) with the pentaspline pulsed field ablation (PFA) catheterconsecutive patients treated with the new olive strategy
Participants
400 patients
Comparison
Olive strategy vs conventional strategy
  • Olive strategyn = 400
Outcome
PV reconnection in patients undergoing repeat procedures
Methodological detailsconsecutive patients, propensity score-matched comparison
  • Consecutive patients
  • Propensity score-matched comparison

Main finding

As reported in the abstract

P = 0.007

Further findings

Freedom of arrhythmia · 180 days after the procedure · no difference

P = 0.75

  • Freedom of arrhythmia: 100 patients treated with the olive strategy vs 100 propensity score-matched conventional patients

Safety

Procedure-related complications — olive strategy
2.75%

Original publication

The Olive Strategy: Improved Pulmonary Vein Isolation Durability With the Pentaspline Pulsed Field Catheter. JACC Clin Electrophysiol. Published 1 April 2025. doi:10.1016/j.jacep.2025.02.026

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