The patient journey in chronic coronary syndromes with/without obstructive coronary arteries
Authors' conclusion
Although the pre-angiography journey (symptoms and non-invasive ischaemic investigations) of patients with obstructive CAD and ANOCA is indistinguishable, the post-angiography journey is portrayed by a vast diagnostic and treatment gap in those with ANOCA, which needs to be addressed.
Study context
- Population
- Patients undergoing elective invasive coronary angiography for the investigation of angina, with Angina with Non-Obstructive Coronary Arteries (ANOCA) or obstructive coronary artery disease (CAD)2,285 ANOCA and 4087 obstructive CAD consecutive patients
- Participants
- 2,285 vs 4,087
- Exposure
- ANOCA vs. obstructive CAD
- ANOCAn = 2,285
- Obstructive CADn = 4,087
- Outcome
- Chest pain features and non-invasive ischaemic markers at presentation
- Follow-up
- Presentation for elective invasive angiography
Methodological detailsconsecutive patients, CADOSA (Coronary Angiogram Database of South Australia) registry, 2012–2018
- Consecutive patients
- CADOSA (Coronary Angiogram Database of South Australia) registry
- 2012–2018
Main finding
As reported in the abstract
- Indistinguishable between patients with obstructive CAD and ANOCA
Observational data: associations, not effects.
Further findings
Age · presentation · ANOCA younger
P < 0.001
Female sex · presentation · ANOCA more likely to be female
P < 0.001
Cardiac discharge diagnosis · following angiography
Anti-anginal therapy · following angiography
Weekly angina (persistent angina) · over 12 months · same prevalence of persistent angina
Traditional cardiac risk factors · presentation
- Fewer traditional cardiac risk factors in ANOCA
Original publication
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