Heart failure & cardiomyopathies
The ‘Peptide for Life’ Initiative in the Emergency Department Study
Main finding · NP testing in the EDResult — go to the resultAbsolute difference 24.4% 95% CI 20.8%–27.9%Authors' conclusion
By increasing awareness and providing resources, the utilization of NPs increased in the ED, leading to improved diagnostic accuracy and enhanced patient care.
Study context
- Population
- ED patients in Western Balkan countries (Bosnia and Herzegovina, Croatia, Montenegro, North Macedonia, Serbia)
- Participants
- 2,519 patients
- Exposure
- Post-P4L-ED phase vs pre-P4L-ED phase
- Outcome
- Natriuretic peptide (NP) testing in the ED
Methodological detailsbefore-and-after comparison, multicentre, 10 centres in five countries
- Before-and-after comparison
- Multicentre
- 10 centres in five countries
Main finding
As reported in the abstract
Absolute difference
24.4%
95% CI 20.8%–27.9%
P < 0.001
Events by group
Post-P4L-EDvs Pre-P4L-ED
absolute difference 24.4% (95% CI 20.8%–27.9%); P < 0.001
Observational data: associations, not effects.
Further findings
Use of both NPs and echocardiography · significant increase
Prescription of diuretics and SGLT2 inhibitors
- Increased prescription of diuretics and SGLT2 inhibitors in post-P4L-ED phase
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
The ‘Peptide for Life’ Initiative in the Emergency Department Study. ESC Heart Fail. Published 13 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →