Arrhythmias & electrophysiology
The Rate of Asystolic Reflex Syncope Is Not Influenced by Age
Authors' conclusion
The rate of the spontaneous asystolic form of RS documented by ILR is constant at any age >40 years. Conversely, the rate of asystolic syncope induced by HUT is higher in younger patients and decreases with age.
Study context
- Population
- Patients ≥40 years with certain or suspected reflex syncope who received an implantable loop recorder (ILR)201 with asystolic event
- Participants
- 1,046 patients
- Comparison
- Age tertiles: ≤60 vs 61 to 72 vs ≥73 years
- ≤60 yearsn = 64
- 61 to 72 yearsn = 72
- ≥73 yearsn = 65
- Outcome
- Rate of asystole (asystolic syncope >3 s or nonsyncopal asystole >6 s on ILR) in spontaneous reflex syncope
Pooled result
As reported in the abstract
Rate of asystolic events (ILR)
P = 0.99
Further pooled results
Asystolic syncope induced during HUT, by age tertile
- Rate of HUT-induced asystolic syncope in increasing age tertiles (greatly age dependent)
- 31.0%, 12.1%, and 11.1%
- Age-dependence across tertiles
- P = 0.009
- HUT performed in 169 of 201
Original publication
The Rate of Asystolic Reflex Syncope Is Not Influenced by Age. JACC Clin Electrophysiol. Published 17 January 2024. doi:10.
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