Arrhythmias & electrophysiology
Right atrial cardioneuroablation of asystolic reflex syncope
Main finding · Burden of asystolic episodes (>3 s, ILR)Result — go to the resultRelative risk reduction 0.12Authors' conclusion
Right atrial CNA reduced asystolic episodes by 88% and syncopal episodes by 76% during the mid-term follow-up. Adverse events were infrequent and mild.
Study context
- Population
- Patients with severe asystolic reflex syncope identified by implantable loop recorder or tilt testing
- Participants
- 28 patients
- Comparison
- Before vs after right atrial cardioneuroablation (CNA)
- Outcome
- Burden of asystolic episodes (>3 s, ILR)
- Follow-up
- Median 12.5 months
Main finding
As reported in the abstract
Relative risk reduction
0.12
P = 0.0001
Events by group
- Patients with asystole >3 s during follow-up
- 8
Further findings
Burden of syncopal episodes
relative risk reduction 0.24 · P = 0.0001
- Heart rate: Before ablation median 75 (IQR 72–79) bpm
- Heart rate: After ablation median 83 (IQR 78–85) bpm
Safety
Procedural complications and follow-up events
- Procedural complications
- 0
- Pacemaker implantation
- 2
- Redo procedure
- 1
- Mild transient symptoms, none requiring therapy
- 4
- Palpitations
- 3
- Dyspnea
- 1
Original publication
Right atrial cardioneuroablation of asystolic reflex syncope. Heart Rhythm. Published 22 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →