The role of stress cardiovascular magnetic resonance in patients with diabetes mellitus
Authors' conclusion
Stress CMR provides valuable prognostic information in diabetic patients, irrespective of symptoms. Further assessment is needed to determine whether stress CMR should be a standard screening tool for diabetic patients.
Study context
- Population
- Diabetic and non-diabetic patients without known cardiovascular disease referred for stress perfusion cardiovascular magnetic resonance (CMR), 2008–2018eligible patients, 1359 diabetics and 1359 non-diabetics included after matching · diabetics 1,359 · non-diabetics 1,359
- Participants
- 3,485 participants
- Exposure
- diabetic vs. non-diabetic patients and then in symptomatic vs. asymptomatic diabetics
- diabeticsn = 1,359
- non-diabeticsn = 1,359
- Asymptomatic diabeticsn = 255
Methodological detailstwo tertiary centres, consecutive patients
- Two tertiary centres
- Consecutive patients
Main finding
As reported in the abstract
MACE:
- Cardiovascular death
- Non-fatal myocardial infarction
Experienced major adverse cardiovascular events (MACEs)
386
14.2%
Observational data: associations, not effects.
Further findings
Predictors of MACE: extent of ischaemia or late gadolinium enhancement involving ≥3 segments
| Comparison | HR (95% CI) | P value | |
|---|---|---|---|
| Extent of ischaemia · independent predictor | 7.14 (5.01–10.02) | P < 0.001 | |
| Late gadolinium enhancement involving ≥3 segments · independent predictor | 5.03 (3.47–7.29) | P < 0.001 | |
| 0.050.21520Hazard ratio (log scale) |
| Outcome | Estimate | P value |
|---|---|---|
| MACE event rates, asymptomatic vs symptomatic diabetics · similar event rates | P = 0.98 |
Predictors of MACE: extent of ischaemia or late gadolinium enhancement involving ≥3 segments
- No significant differences between diabetics and non-diabetics
Original publication
The role of stress cardiovascular magnetic resonance in patients with diabetes mellitus. Eur Heart J Cardiovasc Imaging. Published 23 August 2025. doi:10.
Summarised from the published abstract; every number is checked against it