Arrhythmias & electrophysiology

The Safety and Efficacy of Epicardial Carbon Dioxide Insufflation Compared With Conventional Epicardial Access

JACC Clin ElectrophysiolPublished Retrospective cohort study

Authors' conclusion

EpiCO2 access is associated with lower rates of major complication and bleeding when compared with ConvEpi access.

Study context

Population
Patients undergoing epicardial access (VT ablation), single high-volume center, January 2021–December 202317 operators
Participants
153 patients
Exposure
EpiCO2 vs Conventional Epi (ConvEpi) access
  • EpiCO2n = 73
  • ConvEpin = 80reference
Outcome
Feasibility (access success) and safety of epicardial access
Methodological detailssingle-centre, high-volume center, operator discretion
  • Single-centre
  • High-volume center
  • Operator discretion

Main finding

As reported in the abstract

Epicardial (Epi) access success

P = 0.4

Observational data: associations, not effects.

Further findings

Total Epi access time · shorter with ConvEpi

P < 0.001

Total procedure duration

Total procedure duration similar

Safety

Major Epi access-related complications

P = 0.02

Bleeding ≥80 mL — ConvEpi vs EpiCO2 · unadjusted

P = 0.02

OutcomeOR (95% CI)P value
Bleeding ≥80 mLEpiCO2vs ConvEpiAdjusted for age, repeat Epi access, antithrombotic therapy0.27 (0.08–0.89)P = 0.03

Original publication

The Safety and Efficacy of Epicardial Carbon Dioxide Insufflation Compared With Conventional Epicardial Access. JACC Clin Electrophysiol. Published 16 May 2024. doi:10.1016/j.jacep.2024.05.004

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