Arrhythmias & electrophysiology

Transatrial pericardial insufflation of carbon dioxide to facilitate epicardial mapping and ablation of atrial and ventricular arrhythmias

Heart RhythmPublished retrospective study

Authors' conclusion

TAPI-CO2 is a feasible, efficient, and relatively safe technique for facilitating EA. It provides a simplified alternative to CO2 insufflation through the coronary sinus. Further studies are needed to confirm these results and to identify the populations of patients that would benefit most from this technique.

Study context

Population
All patients undergoing epicardial access (EA) with Transatrial pericardial insufflation of CO2 (TAPI-CO2) at a tertiary care center between December 2020 and November 2024patients included · atrial arrhythmias 6 · ventricular arrhythmias 9
Participants
15 patients
Outcome
TAPI-CO2 successfully performed
Methodological detailstertiary care center
  • Tertiary care center

Main finding

As reported in the abstract

TAPI-CO2

93.3%

14 of Fifteen

Observational data: associations, not effects.

Further findings

OutcomeValues
Subxiphoid EA achievedTAPI-CO2 86.7%
Major adhesionsTAPI-CO2 13.3%
Procedural duration and fluoroscopy timeTAPI-CO2 Procedural duration 265 minutes (interquartile range, 190-288 minutes) · Fluoroscopy time 28 minutes (interquartile range, 24-32 minutes)

Safety

OutcomeValues
Delayed pericardial effusion related to TAPI-CO2TAPI-CO2 6.7%

Delayed pericardial effusion related to TAPI-CO2

1 patient (6.7%)
No patient required surgery

Original publication

Transatrial pericardial insufflation of carbon dioxide to facilitate epicardial mapping and ablation of atrial and ventricular arrhythmias. Heart Rhythm. Published 20 March 2025. doi:10.1016/j.hrthm.2025.03.1967

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