Coronary disease & ACS

Three-Dimensional CT for Preprocedural Planning of PCI for Ostial Right Coronary Artery Lesions: A Randomized Controlled Pilot Trial

Circ Cardiovasc IntervPublished single-center, prospective, open-label, core-laboratory blinded trial

Corrected 23 Oct 2026: Outcome relabelled as geographic mismatch: the control group’s 5 (33%) are patients with mismatch, as the abstract states; no number changed.

Authors' conclusion

Preprocedural 3DCT planning for percutaneous coronary intervention of aorto-ostial right coronary artery lesions allows for optimal stent positioning while reducing procedure time, contrast, and radiation dose.

Study context

Population
Patients with an aorto-ostial right coronary artery lesionpatients randomly assigned
Participants
30 patients
Exposure
Percutaneous coronary intervention with a preprocedural 3DCT or angiography-guided percutaneous coronary intervention
Outcome
percentage of patients without geographic mismatch, as determined by intravascular ultrasound
Methodological detailsrandomly assigned, pilot
  • Randomly assigned
  • Pilot

Main finding

As reported in the abstract

Intervention group

stent in the optimal position in all patients (no mismatch)

Control group

33%

5 events

P = 0.06

Observational data: associations, not effects.

Further findings

OutcomeP value
Procedural contrast, radiation and procedure timeIntervention group vs control group · lower in the intervention groupP < 0.0001
Procedural contrast, radiation and procedure timeIntervention group vs control group · lower in the intervention groupP = 0.03
Procedural contrast, radiation and procedure timeIntervention group vs control group · lower in the intervention groupP = 0.03

C-arm angles

3DCT-determined C-arm angles were heterogenous but, in general, more extreme left anterior oblique projections were used
P < 0.0001

3DCT prediction of calcium arc and minimal lumen area by intravascular ultrasound

Calcium arc
P < 0.0001
Minimal lumen area by intravascular ultrasound
P = 0.003

Original publication

Three-Dimensional CT for Preprocedural Planning of PCI for Ostial Right Coronary Artery Lesions: A Randomized Controlled Pilot Trial. Circ Cardiovasc Interv. Published 29 January 2025. doi:10.1161/circinterventions.123.013584

Composed by AI from the published abstract and checked against it. How Briefs are made →

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