Arrhythmias & electrophysiologyCohort study
Three-dimensional intracardiac echocardiography for left atrial appendage sizing and percutaneous occlusion guidance
- Observational cohort study
Authors' conclusion
Intracardiac echocardiography-guided LAAO showed a very high success, with no major adverse events. A very high level of agreement for LAA sizing was found between pre-procedural TEE and periprocedural 3D-ICE. 3D-ICE performed significantly better than 2D-ICE for FLX size selection and may provide better guidance during device deployment.
Study context
- Population
- Patients undergoing left atrial appendage occlusion (LAAO) with a Watchman FLX
- Participants
- 274 patients
- Exposure
- 3D-ICE vs 2D-ICE guidance of LAAO
- 3D-ICEn = 54
- 2D-ICEn = 220reference
- Outcome
- Composite of:
- Procedural success
- Left atrial appendage (LAA) sealing at follow-up TEE
Main finding
As reported in the abstract
P = 0.99
Observational data: associations, not effects.
Secondary outcomes
Secondary endpoint: periprocedural device recapture/resizing plus leaks ≥ 3 mm at follow-up TEE
P = 0.065
Agreement between ICE-based device selection and final device size
P = 0.005
Periprocedural device recapture/redeployment · trend
P = 0.09
- Correlation of 3D-ICE maximum landing zone with pre-procedural transoesophageal echocardiography (TEE)
- 0.94 · Pearson's · bias −0.06 (−2.39, 2.27)
- Correlation of 3D-ICE maximum landing zone with pre-procedural TEE: P < 0.001
Original publication
Summarised from the published abstract; every number is checked against it