Three-year outcomes of A Randomized Multicentre Trial Comparing Revascularization and Optimal Medical Therapy for Chronic Total Coronary Occlusions (EuroCTO)
Authors' conclusion
At 3 years there was no difference in the rate of cardiovascular death or myocardial infarction between PCI or OMT among patients with a remaining single coronary CTO. The MACE rate was higher in the OMT group due largely to ischaemia-driven revascularisation.
Study context
- Population
- Patients with a symptomatic CTO; non-CTO lesions treated before randomisation
- Participants
- 396 patients
- Comparison
- Percutaneous coronary intervention (PCI) vs optimal medical therapy (OMT) for CTO
- Primary endpoint
- CV death or nonfatal MI
- Follow-up
- 3 years
Methodological detailsmulticentre, 3-year follow-up
- Multicentre
- 3-year follow-up
Primary result
As reported in the abstract
P = 0.29
Further findings
CV death or nonfatal MI, per-protocol analysis · 3 years · non-significant · per-protocol analysis
P = 0.67
MACE · 3 years
Major adverse cardiovascular events (MACE) · 3 years
- More frequent with OMT, largely because of ischaemia-driven revascularisation
Safety
Stroke or hospitalisation for bleeding · 3 years
- Not different between the groups
Original publication
Three-year outcomes of A Randomized Multicentre Trial Comparing Revascularization and Optimal Medical Therapy for Chronic Total Coronary Occlusions (EuroCTO). EuroIntervention. Published 18 September 2023. doi:10. 4244/ eij-d-23-00312
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