Prevention & lipids

Time Trends in Cardiovascular Disease Mortality Across the BRICS: An Age-Period-Cohort Analysis of Key Nations With Emerging Economies Using the Global Burden of Disease Study 2017

CirculationPublished Age-period-cohort analysis of Global Burden of Disease data

Authors' conclusion

Except for Brazil, reductions of CVD mortality across the BRICS have been less than that in North America, such that China, India, and South Africa contribute an increasing proportion of global CVD deaths.

Study context

Population
Brazil, Russia, India, China and South Africa (BRICS), 1992–2016
Outcome
CVD mortality trends (age, period and birth cohort effects)
Follow-up
1992–2016
Methodological detailsage-period-cohort modeling, Mortality estimates from the Global Burden of Disease Study 2017
  • Age-period-cohort modeling
  • Mortality estimates from the Global Burden of Disease Study 2017

Main finding

As reported in the abstract

CVD age-standardized mortality rate change

BRICS

−17%

North America

−39%

Cardiovascular disease (CVD) deaths across the BRICS in 2016
8.4 million
Share of increased all-cause deaths from increase in CVD deaths
Eighty-eight percent
Ischemic heart disease age-standardized mortality increased slightly
2%

Observational data: associations, not effects.

Further findings

Improving period and cohort risks generally, except worsening period effects in India and greater IHD risks in Chinese cohorts born in the 1950s and 1960s

Original publication

Time Trends in Cardiovascular Disease Mortality Across the BRICS: An Age-Period-Cohort Analysis of Key Nations With Emerging Economies Using the Global Burden of Disease Study 2017. Circulation. Published 16 January 2020. doi:10.1161/circulationaha.119.042864

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