TIMI Frame Count and Coronary Function in Women With Suspected Ischemia and Nonobstructed Coronary Arteries
Authors' conclusion
Among women with suspected INOCA, measuring the TFC poststress did not help in the identification of abnormal coronary physiology pathways. Other strategies should be developed to improve accessibility to coronary function testing in this population.
Study context
- Population
- Women with suspected ischemia and no obstructed coronary arteries (INOCA) enrolled in the WISE-CVD studywomen in whom TIMI frame count (TFC) was quantified
- Participants
- 75 women
- Comparison
- TFC with measurements of coronary function
- Outcome
- Baseline characteristics
Methodological detailsrandomly selected subgroup, linear regression
- Randomly selected subgroup
- Linear regression
Main finding
As reported in the abstract
- Mean age
- 54 ± 12 years
- Hypertension
- 29 (42%)
- Diabetes
- 7 (10%)
- Previous smoking history
- 34 (48%)
- Coronary atherosclerosis
- 33 (49%)
Further findings
TFC poststress vs coronary flow reserve and ΔNTG
- Minor positive correlations linking higher TFC poststress with higher coronary flow reserve and higher ΔNTG
- P < 0.05
TFC rest-to-stress ratio postacetylcholine and ΔNTG
- Minor inverse correlations
- P < 0.05
Original publication
TIMI Frame Count and Coronary Function in Women With Suspected Ischemia and Nonobstructed Coronary Arteries. JACC Adv. Published 20 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →