Transcatheter Edge-to-Edge Repair in Papillary Muscle Injury Complicating Acute Myocardial Infarction
Authors' conclusion
TEER is a feasible therapy in critically ill patients with PMR due to a recent MI.
Study context
- Population
- Patients with post-MI papillary muscle rupture (complete, partial or chordal) treated with TEER as salvage, IREMMI registry, Europe, North America and Middle East20 [87%] in cardiogenic shock
- Participants
- 23 patients
- Outcome
- Feasibility of TEER: immediate and 30-day outcomes
- Follow-up
- Immediate and 30 days
Methodological detailsmulticentre, 30 centres, TEER performed median 6 days (IQR 3, 11) after index myocardial infarction (MI)
- Multicentre
- 30 centres
- TEER performed median 6 days (IQR 3, 11) after index MI
Main finding
As reported in the abstract
immediate
- Procedural success
- 87%
- Mitral regurgitation (MR) reduced to 0 or 1+
- 13 (57%)
- MR reduced to 2+
- 7 (30%)
- MR grade significantly decreased after the procedure
- P < 0.01
Observational data: associations, not effects.
Further findings
V-wave, pre- to post-procedure
- V-wave reduced from 49 ± 8 mmHg to 26 ± 10 mmHg
- P < 0.01
Discharged from hospital
- Discharged from hospital
- 16/23 (70%)
- Reintervention with surgical MV replacement among discharged
- 5
Additional death at 1 year
- No additional death at 1 year documented
Original publication
Transcatheter Edge-to-Edge Repair in Papillary Muscle Injury Complicating Acute Myocardial Infarction. ESC Heart Fail. Published 1 February 2024. doi:10.
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