Valvular & structural heart disease
Transcatheter Tricuspid Valve Intervention Risk Scores: Assessment in an International Multicenter Cohort
Authors' conclusion
The currently available TTVI risk scores derived from surgical or early TTVI cohorts may not be well suited for accurate risk assessment in contemporary TTVI. The surgical scores when applied to TTVI are miscalibrated, and the TRIVALVE score lacks discrimination.
Study context
- Population
- Patients undergoing transcatheter tricuspid valve intervention (TTVI) (tricuspid TEER, transcatheter tricuspid valve replacement or annuloplasty), 2019–2024
- Participants
- 457 patients6 international centres
- Exposure
- TTVI risk scores (TRI-SCORE) vs STS-TR vs TRIVALVE risk scores
- Outcome
- Discrimination (C statistic) and calibration of each score for its endpoint
Methodological detailsmulticentre, 6 international centres, risk score validation
- Multicentre
- 6 international centres
- Risk score validation
Main finding
As reported in the abstract
Risk score performance
| Group | AUC | Observed-to-expected mortality ratio |
|---|---|---|
| TRIVALVE | 0.609 | |
| TRI-SCORE | 0.13 (95% CI: 0.07-0.23) | |
| STS-TR | 0.35 (95% CI: 0.19-0.60) |
AUC
TRIVALVE0.609
TRI-SCORE— not stated in the abstract
STS-TR— not stated in the abstract
Observed-to-expected mortality ratio
TRIVALVE— not stated in the abstract
TRI-SCORE0.13 (95% CI: 0.07-0.23)
STS-TR0.35 (95% CI: 0.19-0.60)
Observational data: associations, not effects.
Original publication
Transcatheter Tricuspid Valve Intervention Risk Scores: Assessment in an International Multicenter Cohort. JACC Cardiovasc Interv. Published 23 March 2026. doi:10. 1016/ j. jcin. 2025. 12. 020
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