Valvular & structural heart diseaseCohort study
Transcatheter Tricuspid Valve Replacement and CLEFT After Tricuspid TEER
- Case series
Authors' conclusion
At 30 days, TR severity was markedly reduced, and substantial symptom alleviation occurred.
Study context
- Population
- Patients with severe, symptomatic tricuspid regurgitation (TR) after tricuspid transcatheter edge-to-edge repair8 with leaflet modification
- Participants
- 16 patients
- Exposure
- Transcatheter tricuspid valve replacement (TTVR) after tricuspid transcatheter edge-to-edge repair (T-TEER), with or without CLEFT
- TTVR after T-TEERn = 16
- Outcome
- Procedural technical success
Main finding
As reported in the abstract
Procedural technical success rate
93.7% (15 of 16; 95% CI 69.8%-99.8%)
Observational data: associations, not effects.
Secondary outcomes
Survival to 30 days
- Survival to 30 days (15 of 16)
- 93.7%
NYHA class I or II · 30 days
- NYHA class I or II improved (13 of 16) vs baseline
- 86.7%
- P < 0.001 compared with baseline
TR severity · 30 days
- TR severity reduced; no or mild TR
- 93.3%
- P < 0.001
Original publication
Transcatheter Tricuspid Valve Replacement and CLEFT After Tricuspid TEER. JACC Cardiovasc Interv. Published 25 October 2025. doi:10.1016/j.jcin.2025.10.001
Summarised from the published abstract; every number is checked against it