Heart failure & cardiomyopathies

Transition from Asymptomatic to Symptomatic Systolic Chronic Heart Failure: Rationale and Design of TransitionCHF

ESC Heart FailPublished Prospective cohort study

Study context

Population
Patients with asymptomatic systolic dysfunction (New York Heart Association (NYHA) I) and LVEF ≤40%, incidental findings or asymptomatic after a previous symptomatic eventrecruited
Participants
1,000 patients
Primary endpoint
Time to HF hospitalization and CV death (composite)
Methodological detailsrationale and design, multicentre, longitudinal, 20 university HF clinics across Germany, Annual follow-up over the course of the study
  • Rationale and design
  • Multicentre
  • Longitudinal
  • 20 university HF clinics across Germany
  • Annual follow-up over the course of the study

No results yet. This paper sets out the design of a trial; its results are to come.

Original publication

Transition from Asymptomatic to Symptomatic Systolic Chronic Heart Failure: Rationale and Design of TransitionCHF. ESC Heart Fail. Published 12 April 2024. doi:10.1002/ehf2.14783

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